Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Others
SUBMITTER: Anna Santamaria
PROVIDER: PAe005279 | PeptideAtlas | 2011-12-31
REPOSITORIES: PeptideAtlas
Items per page: 1 - 5 of 8 |

Molecular & cellular proteomics : MCP 20100922 1
Polo-like kinases regulate many aspects of mitotic and meiotic progression from yeast to man. In early mitosis, mammalian Polo-like kinase 1 (Plk1) controls centrosome maturation, spindle assembly, and microtubule attachment to kinetochores. However, despite the essential and diverse functions of Plk1, the full range of Plk1 substrates remains to be explored. To investigate the Plk1-dependent phosphoproteome of the human mitotic spindle, we combined stable isotope labeling by amino acids in cell ...[more]