Proteomics

Dataset Information

0

HS_Plk1_Specific_Phos_SILAC


ABSTRACT: HS_Plk1_Specific_Phosphosites_SILAC

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Others

SUBMITTER: Anna Santamaria 

PROVIDER: PAe005279 | PeptideAtlas | 2011-12-31

REPOSITORIES: PeptideAtlas

Dataset's files

Source:
Action DRS
PAe005279_10308_tandem.params Other
PAe005279_README Other
PAe005279_Search_Results_10308_201601041507.properties Other
PAe005279_Search_Results_10308_201601041507.tar.gz Other
PAe005279_mzXML_201601041449.properties Other
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Publications

The Plk1-dependent phosphoproteome of the early mitotic spindle.

Santamaria Anna A   Wang Bin B   Elowe Sabine S   Malik Rainer R   Zhang Feng F   Bauer Manuel M   Schmidt Alexander A   Silljé Herman H W HH   Körner Roman R   Nigg Erich A EA  

Molecular & cellular proteomics : MCP 20100922 1


Polo-like kinases regulate many aspects of mitotic and meiotic progression from yeast to man. In early mitosis, mammalian Polo-like kinase 1 (Plk1) controls centrosome maturation, spindle assembly, and microtubule attachment to kinetochores. However, despite the essential and diverse functions of Plk1, the full range of Plk1 substrates remains to be explored. To investigate the Plk1-dependent phosphoproteome of the human mitotic spindle, we combined stable isotope labeling by amino acids in cell  ...[more]

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