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Hs_heLa_phospho_Orbi

ABSTRACT: Hs_heLa_phospho_Orbi

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Lung

DISEASE(S): Non-small Cell Lung Carcinoma

SUBMITTER: Michael J. Comb

PROVIDER: PAe005322 | PeptideAtlas | 2006-12-31

REPOSITORIES: PeptideAtlas

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Publications

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

Beausoleil Sean A SA Villén Judit J Gerber Scott A SA Rush John J Gygi Steven P SP

Nature biotechnology 20060910 10

Data analysis and interpretation remain major logistical challenges when attempting to identify large numbers of protein phosphorylation sites by nanoscale reverse-phase liquid chromatography/tandem mass spectrometry (LC-MS/MS) (Supplementary Figure 1 online). In this report we address challenges that are often only addressable by laborious manual validation, including data set error, data set sensitivity and phosphorylation site localization. We provide a large-scale phosphorylation data set wi ...[more]

PMID: 16964243

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