Proteomics

Dataset Information

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Hs_C-HPP_EnrichmentStrategy_LMW_Proteominer


ABSTRACT: Enrichment strategy for searching missing protein, LMW Proteins, Proteominer

REANALYSIS of: PXD002255

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Plasma Non-glyco

SUBMITTER: Su N, Zhang C, Zhang Y, Wang Z, Fan F, Zhao M, Wu F, Gao Y, Li Y, Chen L, Tian M, Zhang T, Wen B, Sensang N, Xiong Z, Wu S, Liu S, Yang P, Zhen B, Zhu Y, He F, Xu P 

PROVIDER: PAe005415 | PeptideAtlas | 2015-12-31

REPOSITORIES: PeptideAtlas

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Publications

Special Enrichment Strategies Greatly Increase the Efficiency of Missing Proteins Identification from Regular Proteome Samples.

Su Na N   Zhang Chengpu C   Zhang Yao Y   Wang Zhiqiang Z   Fan Fengxu F   Zhao Mingzhi M   Wu Feilin F   Gao Yuan Y   Li Yanchang Y   Chen Lingsheng L   Tian Miaomiao M   Zhang Tao T   Wen Bo B   Sensang Na N   Xiong Zhi Z   Wu Songfeng S   Liu Siqi S   Yang Pengyuan P   Zhen Bei B   Zhu Yunping Y   He Fuchu F   Xu Ping P  

Journal of proteome research 20150715 9


As part of the Chromosome-Centric Human Proteome Project (C-HPP) mission, laboratories all over the world have tried to map the entire missing proteins (MPs) since 2012. On the basis of the first and second Chinese Chromosome Proteome Database (CCPD 1.0 and 2.0) studies, we developed systematic enrichment strategies to identify MPs that fell into four classes: (1) low molecular weight (LMW) proteins, (2) membrane proteins, (3) proteins that contained various post-translational modifications (PTM  ...[more]

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