Models

Dataset Information

0

Vasalou and Henson 2010

ABSTRACT: This workspace contains SED-ML and cellml files that reproduces the results shown in the original paper.

SUBMITTER: David Nickerson  

PROVIDER: 2f1 | Physiome Model Repository |

REPOSITORIES: PMR

Json Xml
altmetric image

Publications

A multiscale model to investigate circadian rhythmicity of pacemaker neurons in the suprachiasmatic nucleus.

Vasalou Christina C   Henson Michael A MA  

PLoS computational biology 20100312 3

The suprachiasmatic nucleus (SCN) of the hypothalamus is a multicellular system that drives daily rhythms in mammalian behavior and physiology. Although the gene regulatory network that produces daily oscillations within individual neurons is well characterized, less is known about the electrophysiology of the SCN cells and how firing rate correlates with circadian gene expression. We developed a firing rate code model to incorporate known electrophysiological properties of SCN pacemaker cells,  ...[more]

Similar Datasets

Models Bonhoeffer, Rembiszewski, Ortiz, Nixon, 2000
| 2dc | Physiome Model Repository
Models Li, Bertram and Rinzel, 1996
| 2ea | Physiome Model Repository
Models Goldbeter Dupont Berridge 1990
| 35a | Physiome Model Repository
Models Tabak, Mascagni and Bertram 2010
| 2f0 | Physiome Model Repository
Models Ciliberto, Novak, Tyson, 2003
| 36c | Physiome Model Repository
Models Cui, Kaandorp, 2006
| 354 | Physiome Model Repository
Genomics ChIP-chip of 38 nuclear receptors and NR co-factors in breast cancer cell line MCF7
2013-01-01 | GSE41995 | GEO
Models Chen, Csikasz-Nagy, Gyorffy, Val, Novak, Tyson, 2000
| 36a | Physiome Model Repository
Models Ciliberto, Petrus, Tyson, Sible, 2003
| 36d | Physiome Model Repository
Models Purvis, Butera, 2005
| 2ee | Physiome Model Repository