Proteomics

Dataset Information

0

Longitudinal Olink affinity proteomics profiling of cytokine release syndrome in myeloma patients receiving BCMA-directed CAR-T therapy


ABSTRACT: This submission contains de-identified Olink NPX affinity proteomics data from longitudinal peripheral blood samples collected from patients with relapsed/refractory multiple myeloma treated with BCMA-directed CAR-T therapy (ide-cel or cilta-cel) in a prospective single-center pilot study. Samples were analyzed using the Olink Target 92 Immuno-Oncology panel to characterize inflammatory protein dynamics associated with cytokine release syndrome (CRS). In the associated study, these proteomic data were integrated with wearable physiologic monitoring to evaluate early CRS detection and to identify candidate biomarkers, including IFN-γ.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Plasma

DISEASE(S): Multiple Myeloma

SUBMITTER: Alessandro Lagana'  

LAB HEAD: Alessandro Lagana'

PROVIDER: PAD000041 | Pride | 2026-04-28

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
ADRO04_IO_All_Plates_01082024_Ct.raw.csv Csv
Olink_combined.long.npx.csv Csv
checksum.txt Txt
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