Dataset Information
Candida glabrata secreted proteins - regulation by ACE2 transcription factor
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Bruker Daltonics HCT Series, instrument model
ORGANISM(S): Candida Glabrata (yeast) (torulopsis Glabrata)
TISSUE(S): Culture Supernatant, Stationary Phase Culture
SUBMITTER: 
David Stead
PROVIDER: PRD000038 | Pride | 2010-01-12
REPOSITORIES: Pride
Publications
Impact of the transcriptional regulator, Ace2, on the Candida glabrata secretome.
Proteomics 20100101 2
Candida glabrata is a major fungal pathogen of humans, and the virulence of C. glabrata is increased by inactivation of the transcription factor, Ace2. Our previous examination of the effects of Ace2 inactivation upon the intracellular proteome suggested that the hypervirulence of C. glabrata ace2 mutants might be caused by differences in the secretome. Therefore in this study we have characterised the C. glabrata secretome and examined the effects of Ace2 inactivation upon this extracellular pr ...[more]
