Proteomics

Dataset Information

0

HUPO Kidney and Urine Proteome Project


ABSTRACT: Not available

INSTRUMENT(S): instrument model, Agilent instrument model

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Renal Glomerulus

SUBMITTER: Tadashi Yamamoto  

PROVIDER: PRD000042 | Pride | 2008-08-08

REPOSITORIES: Pride

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Publications

In-depth proteomic profiling of the normal human kidney glomerulus using two-dimensional protein prefractionation in combination with liquid chromatography-tandem mass spectrometry.

Miyamoto Masahito M   Yoshida Yutaka Y   Taguchi Izumi I   Nagasaka Yoshimi Y   Tasaki Masayuki M   Zhang Ying Y   Xu Bo B   Nameta Masaaki M   Sezaki Hiroshi H   Cuellar Lino M LM   Osawa Tetsuo T   Morishita Hideo H   Sekiyama Shigeki S   Yaoita Eishin E   Kimura Kenjiro K   Yamamoto Tadashi T  

Journal of proteome research 20070821 9


The kidney glomerulus plays a pivotal role in ultrafiltration of plasma into urine and also is the locus of kidney disease progressing to chronic renal failure. We have focused proteomic analysis on the glomerulus that is most proximal to the disease locus. In the present study, we aimed to provide a confident, in-depth profiling of the glomerulus proteome. The glomeruli were highly purified from the kidney cortex from a male, 68-year-old patient who underwent nephroureterectomy due to ureter ca  ...[more]

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