Name: Fossil bone sequencing - Protein sequences from mastodon and Tyrannosaurus rex revealed by mass spectrometry
Keywords: Not available

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Fossil bone sequencing - Protein sequences from mastodon and Tyrannosaurus rex revealed by mass spectrometry

ABSTRACT: Not available

INSTRUMENT(S): instrument model, LTQ

ORGANISM(S): Struthio Camelus (ostrich)

SUBMITTER: John Asara

PROVIDER: PRD000085 | Pride | 2009-07-28

REPOSITORIES: Pride

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Protein sequences from mastodon and Tyrannosaurus rex revealed by mass spectrometry.

Asara John M JM Schweitzer Mary H MH Freimark Lisa M LM Phillips Matthew M Cantley Lewis C LC

Science (New York, N.Y.) 20070401 5822

Fossilized bones from extinct taxa harbor the potential for obtaining protein or DNA sequences that could reveal evolutionary links to extant species. We used mass spectrometry to obtain protein sequences from bones of a 160,000- to 600,000-year-old extinct mastodon (Mammut americanum) and a 68-million-year-old dinosaur (Tyrannosaurus rex). The presence of T. rex sequences indicates that their peptide bonds were remarkably stable. Mass spectrometry can thus be used to determine unique sequences ...[more]

PMID: 17431180

Publication: 1/2

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