Dataset Information
Quantitative erythrocyte membrane proteome analysis with Blue-Native SDS PAGE
Ontology highlight
ABSTRACT:
INSTRUMENT(S): instrument model, LTQ
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Red Blood Cell
SUBMITTER: 
Henk W.P. van den Toorn
PROVIDER: PRD000092 | Pride | 2011-04-15
REPOSITORIES: Pride
Publications
Quantitative erythrocyte membrane proteome analysis with Blue-native/SDS PAGE.
Journal of proteomics 20090921 3
The erythrocyte membrane plays a pivotal role in erythrocyte functioning. Many membrane protein aberrations are known that result in hemolytic anemia, however, the origin of numerous disorders is not known to date. To extend the current set of diagnostic tools, we used a novel proteome-wide approach to quantitatively analyze membrane proteins of healthy donor and patient erythrocytes. Blue-native PAGE has proven to be a powerful tool for separation of membrane proteins and their complexes, but h ...[more]
