Proteomics,Multiomics

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PH stress - Functional genomics of pH homeostasis in Corynebacterium glutamicum revealed novel links between pH response, oxidative stress, iron homeostasis and methionine synthesis


ABSTRACT: Not available

INSTRUMENT(S): LTQ Orbitrap, instrument model

ORGANISM(S): Corynebacterium Glutamicum Atcc 13032

SUBMITTER: Christian Troetschel  

PROVIDER: PRD000109 | Pride | 2010-01-06

REPOSITORIES: Pride

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Publications

Functional genomics of pH homeostasis in Corynebacterium glutamicum revealed novel links between pH response, oxidative stress, iron homeostasis and methionine synthesis.

Follmann Martin M   Ochrombel Ines I   Krämer Reinhard R   Trötschel Christian C   Poetsch Ansgar A   Rückert Christian C   Hüser Andrea A   Persicke Marcus M   Seiferling Dominic D   Kalinowski Jörn J   Marin Kay K  

BMC genomics 20091221


<h4>Background</h4>The maintenance of internal pH in bacterial cells is challenged by natural stress conditions, during host infection or in biotechnological production processes. Comprehensive transcriptomic and proteomic analyses has been conducted in several bacterial model systems, yet questions remain as to the mechanisms of pH homeostasis.<h4>Results</h4>Here we present the comprehensive analysis of pH homeostasis in C. glutamicum, a bacterium of industrial importance. At pH values between  ...[more]

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