Targetting the Glycolytic Proteome
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Qtrap
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: 
Patrick Murphy
LAB HEAD: Patrick Murphy
PROVIDER: PRD000258 | Pride | 2010-11-23
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| PRIDE_Exp_Complete_Ac_12915.pride.mgf.gz | Mgf | |||
| PRIDE_Exp_Complete_Ac_12915.pride.mztab.gz | Mztab | |||
| PRIDE_Exp_Complete_Ac_12915.xml.gz | Xml |
Items per page: 5 1 - 3 of 3 |
Publications
Targeted proteomic analysis of glycolysis in cancer cells.
Murphy J Patrick JP Pinto Devanand M DM
Journal of proteome research 20101122 2
Altered expression of glycolysis proteins is an important yet poorly understood characteristic of cancer. To better understand the glycolytic changes during tumorigenesis, we designed a liquid chromatography multiple reaction monitoring (LC-MRM) assay targeting the "glycolysis proteome" in MCF-7 breast cancer cells, using isotope-coded dimethylation of peptides for relative quantification. In silico, dimethyl labeled tryptic peptides [M + 2H](2+) (of length n) and their y(n-1) fragment ions were ...[more]
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