Dataset Information
Coxiella Burnetii - Identification of potentially involved proteins in levofloxacin resistance mechanisms in Coxiella burnetii
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ-Orbitrap
ORGANISM(S): Coxiella Burnetii
SUBMITTER: 
Pieter-Jan De Bock
LAB HEAD: Pieter-Jan De Bock
PROVIDER: PRD000262 | Pride | 2012-07-20
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| PRIDE_Exp_Complete_Ac_13081.pride.mgf.gz | Mgf | |||
| PRIDE_Exp_Complete_Ac_13081.pride.mztab.gz | Mztab | |||
| PRIDE_Exp_Complete_Ac_13081.xml.gz | Xml |
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Publications
Identification of potentially involved proteins in levofloxacin resistance mechanisms in Coxiella burnetii.
Journal of proteome research 20101207 2
The etiological agent of Q fever, Coxiella burnetii, is an obligate intracellular bacterium that multiplies within a phagosome-like parasitophorous vacuole. Fluoroquinolones have been used as an alternative therapy for Q fever. Resistance to fluoroquinolones can arise via several mechanisms utilized by pathogens to avoid killing. Until today, genome-based studies have shown that the main mechanism of C. burnetii to resist inhibition by fluoroquinolones is based on mutations in quinolone-resistan ...[more]
