Dataset Information

Planarian Neoblast Proteomics - A proteomics approach to decipher the molecular nature of planarian stem cells

ABSTRACT: We have developed an accurate and reliable mass-spectra-based proteomics approach to complement previous genomic studies and to further achieve a more accurate understanding and description of the molecular and cellular processes related to the neoblasts.

INSTRUMENT(S): 4700 Proteomic Analyzer

ORGANISM(S): Schmidtea Mediterranea (freshwater Planarian Flatworm)

SUBMITTER: Josep F Abril

LAB HEAD: Josep F Abril

PROVIDER: PRD000350 | Pride | 2012-03-05

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	PRIDE_Exp_Complete_Ac_15541.pride.mgf.gz	Mgf
	PRIDE_Exp_Complete_Ac_15541.xml.gz	Xml

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Publications

A proteomics approach to decipher the molecular nature of planarian stem cells.

Fernández-Taboada Enrique E Rodríguez-Esteban Gustavo G Saló Emili E Abril Josep F JF

BMC genomics 20110228

<h4>Background</h4>In recent years, planaria have emerged as an important model system for research into stem cells and regeneration. Attention is focused on their unique stem cells, the neoblasts, which can differentiate into any cell type present in the adult organism. Sequencing of the Schmidtea mediterranea genome and some expressed sequence tag projects have generated extensive data on the genetic profile of these cells. However, little information is available on their protein dynamics.<h4 ...[more]

PMID: 21356107

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