Proteomics

Dataset Information

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Evidence for the presence of disease-perturbed networks in prostate cancer cells by genomic and proteomic analyses

ABSTRACT: Not available

INSTRUMENT(S): ESI-ION-TRAP

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Attila Csordas  

LAB HEAD: Attila Csordas

PROVIDER: PRD000471 | Pride | 2012-07-26

REPOSITORIES: Pride

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PRIDE_Exp_Complete_Ac_17932.pride.mgf.gz Mgf
PRIDE_Exp_Complete_Ac_17932.pride.mztab.gz Mztab
PRIDE_Exp_Complete_Ac_17932.xml.gz Xml
PRIDE_Exp_Complete_Ac_17933.pride.mgf.gz Mgf
PRIDE_Exp_Complete_Ac_17933.pride.mztab.gz Mztab
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Publications

Evidence for the presence of disease-perturbed networks in prostate cancer cells by genomic and proteomic analyses: a systems approach to disease.

Lin Biaoyang B   White James T JT   Lu Wei W   Xie Tao T   Utleg Angelita G AG   Yan Xiaowei X   Yi Eugene C EC   Shannon Paul P   Khrebtukova Irina I   Lange Paul H PH   Goodlett David R DR   Zhou Daixing D   Vasicek Thomas J TJ   Hood Leroy L  

Cancer research 20050401 8

Prostate cancer is initially responsive to androgen ablation therapy and progresses to androgen-unresponsive states that are refractory to treatment. The mechanism of this transition is unknown. A systems approach to disease begins with the quantitative delineation of the informational elements (mRNAs and proteins) in various disease states. We employed two recently developed high-throughput technologies, massively parallel signature sequencing (MPSS) and isotope-coded affinity tag, to gain a co  ...[more]

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