Dataset Information
The application of new software tools to quantitative protein profiling via Isotope-coded Affinity Tag (ICAT) and MS/MS
Ontology highlight
ABSTRACT:
INSTRUMENT(S): ESI-ION-TRAP
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: 
Attila Csordas
LAB HEAD: Attila Csordas
PROVIDER: PRD000495 | Pride | 2012-07-26
REPOSITORIES: pride
Dataset's files
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Publications
The application of new software tools to quantitative protein profiling via isotope-coded affinity tag (ICAT) and tandem mass spectrometry: II. Evaluation of tandem mass spectrometry methodologies for large-scale protein analysis, and the application of statistical tools for data analysis and interpretation.
Molecular & cellular proteomics : MCP 20030625 7
Proteomic approaches to biological research that will prove the most useful and productive require robust, sensitive, and reproducible technologies for both the qualitative and quantitative analysis of complex protein mixtures. Here we applied the isotope-coded affinity tag (ICAT) approach to quantitative protein profiling, in this case proteins that copurified with lipid raft plasma membrane domains isolated from control and stimulated Jurkat human T cells. With the ICAT approach, cysteine resi ...[more]
