Dataset Information
Label free quantitative analysis of brain mitochondrial fraction tumour vs non-tumour
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap, instrument model
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Brain
SUBMITTER: 
Thierry Le Bihan
PROVIDER: PRD000620 | Pride | 2015-09-11
REPOSITORIES: Pride
Publications
Interactions among mitochondrial proteins altered in glioblastoma.
Journal of neuro-oncology 20140413 2
Mitochondrial dysfunction is putatively central to glioblastoma (GBM) pathophysiology but there has been no systematic analysis in GBM of the proteins which are integral to mitochondrial function. Alterations in proteins in mitochondrial enriched fractions from patients with GBM were defined with label-free liquid chromatography mass spectrometry. 256 mitochondrially-associated proteins were identified in mitochondrial enriched fractions and 117 of these mitochondrial proteins were markedly (fol ...[more]
