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EV_Proteome - Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells

ABSTRACT: Extracellular vesicles derived from SW480

INSTRUMENT(S): Thermo Scientific LTQ Orbitrap XL

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Sw-620 Cell, Colorectal Cancer Cell Line, Sw-480 Cell

SUBMITTER: Dong-Sic Choi

LAB HEAD: Dong-Sic Choi

PROVIDER: PRD000647 | Pride | 2013-09-12

REPOSITORIES: Pride

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			Action	DRS
	PRIDE_Exp_Complete_Ac_21768.pride.mgf.gz	Mgf
	PRIDE_Exp_Complete_Ac_21768.pride.mztab.gz	Mztab
	PRIDE_Exp_Complete_Ac_21768.xml.gz	Xml
	PRIDE_Exp_Complete_Ac_21769.pride.mgf.gz	Mgf
	PRIDE_Exp_Complete_Ac_21769.pride.mztab.gz	Mztab

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Publications

Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells.

Choi Dong-Sic DS Choi Do-Young DY Hong Bok Sil BS Jang Su Chul SC Kim Dae-Kyum DK Lee Jaewook J Kim Yoon-Keun YK Kim Kwang Pyo KP Gho Yong Song YS

Journal of extracellular vesicles 20120911

Cancer cells actively release extracellular vesicles (EVs), including exosomes and microvesicles, into surrounding tissues. These EVs play pleiotropic roles in cancer progression and metastasis, including invasion, angiogenesis, and immune modulation. However, the proteomic differences between primary and metastatic cancer cell-derived EVs remain unclear. Here, we conducted comparative proteomic analysis between EVs derived from human primary colorectal cancer cells (SW480) and their metastatic ...[more]

PMID: 24009881

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