Ontology highlight
ABSTRACT:
INSTRUMENT(S): Thermo LTQ-Orbitrap
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell, Cell Culture
SUBMITTER:
Michael Katze
LAB HEAD: Michael Katze
PROVIDER: PRD000671 | Pride | 2012-04-02
REPOSITORIES: Pride
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Journal of virology 20110629 17
The trimeric RNA polymerase complex (3P, for PA-PB1-PB2) of influenza A virus (IAV) is an important viral determinant of pathogenicity and host range restriction. Specific interactions of the polymerase complex with host proteins may be determining factors in both of these characteristics and play important roles in the viral life cycle. To investigate this question, we performed a comprehensive proteomic analysis of human host proteins associated with the polymerase of the well-characterized H5 ...[more]