Proteomics

Dataset Information

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LYSOMB - An extended proteome map of the lysosomal membrane reveals novel potential transporters

ABSTRACT: Comparison between lysosome-enriched and lysosome-partly depleted fractions

INSTRUMENT(S): LTQ-Orbitrap

ORGANISM(S): Rattus Norvegicus (rat)

TISSUE(S): Liver

SUBMITTER: Agnes JOURNET  

LAB HEAD: Agnes JOURNET

PROVIDER: PRD000698 | Pride | 2013-03-05

REPOSITORIES: Pride

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Dataset's files

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Action DRS
PRIDE_Exp_Complete_Ac_22847.pride.mgf.gz Mgf
PRIDE_Exp_Complete_Ac_22847.pride.mztab.gz Mztab
PRIDE_Exp_Complete_Ac_22847.xml.gz Xml
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Publications

An extended proteome map of the lysosomal membrane reveals novel potential transporters.

Chapel Agnès A   Kieffer-Jaquinod Sylvie S   Sagné Corinne C   Verdon Quentin Q   Ivaldi Corinne C   Mellal Mourad M   Thirion Jaqueline J   Jadot Michel M   Bruley Christophe C   Garin Jérôme J   Gasnier Bruno B   Journet Agnès A  

Molecular & cellular proteomics : MCP 20130224 6

Lysosomes are membrane-bound endocytic organelles that play a major role in degrading cell macromolecules and recycling their building blocks. A comprehensive knowledge of the lysosome function requires an extensive description of its content, an issue partially addressed by previous proteomic analyses. However, the proteins underlying many lysosomal membrane functions, including numerous membrane transporters, remain unidentified. We performed a comparative, semi-quantitative proteomic analysis  ...[more]