Proteomics

Dataset Information

0

Proteome of the Human Corpus Callosum

ABSTRACT: Characterization of the human Anterior Temporal Lobe and Corpus Callosum: C-HPP

REANALYSED by: PAe005151

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Corpus Callosum

SUBMITTER: Daniel Martins-de-Souza  

LAB HEAD: Daniel Martins-de-Souza

PROVIDER: PXD000547 | Pride | 2014-06-05

REPOSITORIES: Pride

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Publications

Deciphering the human brain proteome: characterization of the anterior temporal lobe and corpus callosum as part of the Chromosome 15-centric Human Proteome Project.

Martins-de-Souza Daniel D   Carvalho Paulo C PC   Schmitt Andrea A   Junqueira Magno M   Nogueira Fábio C S FC   Turck Christoph W CW   Domont Gilberto B GB  

Journal of proteome research 20131203 1

Defining the proteomes encoded by each chromosome and characterizing proteins related to human illnesses are among the goals of the Chromosome-centric Human Proteome Project (C-HPP) and the Biology and Disease-driven HPP. Following these objectives, we investigated the proteomes of the human anterior temporal lobe (ATL) and corpus callosum (CC) collected post-mortem from eight subjects. Using a label-free GeLC-MS/MS approach, we identified 2454 proteins in the ATL and 1887 in the CC through roug  ...[more]