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Anopheles gambiae brain proteomic analysis

ABSTRACT: Proteomic analysis of Anopheles gambiae brain tissue after in-gel trypsin digestion. To gain insights into neurobiology of the Anopheles gambiae mosquito, we carried out a proteomic analysis of its brain using a comprehensive proteomic approach.

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Anopheles Gambiae Str. Pest

SUBMITTER: Akhilesh Pandey

LAB HEAD: Akhilesh Pandey

PROVIDER: PXD000630 | Pride | 2016-12-20

REPOSITORIES: Pride

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Brain proteomics of Anopheles gambiae.

Dwivedi Sutopa B SB Muthusamy Babylakshmi B Kumar Praveen P Kim Min-Sik MS Nirujogi Raja Sekhar RS Getnet Derese D Ahiakonu Priscilla P De Gourav G Nair Bipin B Gowda Harsha H Prasad T S Keshava TS Kumar Nirbhay N Pandey Akhilesh A Okulate Mobolaji M

Omics : a journal of integrative biology 20140617 7

Anopheles gambiae has a well-adapted system for host localization, feeding, and mating behavior, which are all governed by neuronal processes in the brain. However, there are no published reports characterizing the brain proteome to elucidate neuronal signaling mechanisms in the vector. To this end, a large-scale mapping of the brain proteome of An. gambiae was carried out using high resolution tandem mass spectrometry, revealing a repertoire of >1800 proteins, of which 15% could not be assigned ...[more]

PMID: 24937107

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