Dataset Information
Comparative study of secretomes and vesicular subproteomes from Pseudomonas aeruginosa (PAO1)
Ontology highlight
ABSTRACT:
INSTRUMENT(S): TripleTOF 5600
ORGANISM(S): Pseudomonas Aeruginosa
SUBMITTER: 
Sergio Ciordia
LAB HEAD: Juan Pablo Albar Ramirez
PROVIDER: PXD000687 | Pride | 2018-10-27
REPOSITORIES: Pride
Publications
Quantitative proteomics unravels that the post-transcriptional regulator Crc modulates the generation of vesicles and secreted virulence determinants of Pseudomonas aeruginosa.
Journal of proteomics 20150621 Pt B
Recent research indicates that the post-transcriptional regulator Crc modulates susceptibility to antibiotics and virulence in Pseudomonas aeruginosa. Several P. aeruginosa virulence factors are secreted or engulfed in vesicles. To decipher the Crc modulation of P. aeruginosa virulence, we constructed a crc deficient mutant and measure the proteome associated extracellular vesicles and the vesicle-free secretome using iTRAQ. Fifty vesicle-associated proteins were more abundant and 14 less abunda ...[more]
