Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Suspension Culture, Epithelial Cell
DISEASE(S): Malignant Neoplasm Of Ovary
SUBMITTER: Thomas Kislinger
LAB HEAD: Thomas Kislinger
PROVIDER: PXD000695 | Pride | 2014-01-22
REPOSITORIES: Pride
Sinha Ankit A Ignatchenko Vladimir V Ignatchenko Alex A Mejia-Guerrero Salvador S Kislinger Thomas T
Biochemical and biophysical research communications 20140114 4
Molecular communication between cancer cells and its stromal microenvironment is a key factor for cancer progression. Alongside classic secretory pathways, it has recently been proposed that small membranous vesicles are alternative mediators of intercellular communication. Exosomes carry an effector-rich proteome with the ability to modulate various functional properties of the recipient cell. In this study, exosomes isolated from four epithelial ovarian cancer cell lines (OVCAR3, OVCAR433, OVC ...[more]