Discovery of new cerebrospinal fluid biomarkers for meningitis in children C4PR_LIV

ABSTRACT: Bacterial meningitis is usually fatal without treatment and prompt and accurate diagnosis coupled with the timely administration of parenteral antibiotics, are necessary in order to save lives. The diagnosis can sometimes be delayed whilst samples are analysed in a laboratory using traditional methods of microscopy and antigen testing. The objective of our project is to define specific protein signatures in cerebrospinal fluid associated with Streptococcus pneumoniae infection which could lead to the development of assays or point-of-care devices to improve the speed and accuracy of diagnosis, and guide the clinicians in the treatment and prognosis of children with bacterial meningitis. The associated research paper is in preparation.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human) Streptococcus Pneumoniae (strain Atcc Baa-255 / R6)

TISSUE(S): Cerebrospinal Fluid

SUBMITTER: Da Qi  

LAB HEAD: Rob Beynon

PROVIDER: PXD000764 | Pride | 2014-07-22

REPOSITORIES: Pride