Proteomics

Dataset Information

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Bacillus cereus proteomics - Proteomic Evidences for Rex Regulation of Metabolism in Toxin-Producing Bacillus cereus ATCC 14579

ABSTRACT: This project contributes to the proteomic comparison of Bacillus cereus wild-type and Bacillus cereus mutant devoided of the Rex regulator. Aerobiosis and anaerobiosis conditions were assayed.

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Bacillus Cereus (strain Atcc 14579 / Dsm 31)

SUBMITTER: Jean ARMENGAUD  

LAB HEAD: Jean ARMENGAUD

PROVIDER: PXD000886 | Pride | 2014-09-25

REPOSITORIES: Pride

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Publications

Proteomic evidences for rex regulation of metabolism in toxin-producing Bacillus cereus ATCC 14579.

Laouami Sabrina S   Clair Géremy G   Armengaud Jean J   Duport Catherine C  

PloS one 20140912 9

The facultative anaerobe, Bacillus cereus, causes diarrheal diseases in humans. Its ability to deal with oxygen availability is recognized to be critical for pathogenesis. The B. cereus genome comprises a gene encoding a protein with high similarities to the redox regulator, Rex, which is a central regulator of anaerobic metabolism in Bacillus subtilis and other Gram-positive bacteria. Here, we showed that B. cereus rex is monocistronic and down-regulated in the absence of oxygen. The protein en  ...[more]