Proteomics

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The meiotic proteome in yeast - The protein expression landscape of mitosis and meiosis in diploid budding yeast


ABSTRACT: Dynamic proteome in diploid yeast cells undergoing mitotic growth and meiotic development. The proteome of growing (YPA) and differentiating yeast cells at 6 hours (SPII 6, middle meiosis) and 8 hours (SPII8, late meiosis) were compared using the TOP3 GeLC-MS/MS method.

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)

SUBMITTER: E Com  

LAB HEAD: Charles Pineau

PROVIDER: PXD001275 | Pride | 2017-01-16

REPOSITORIES: Pride

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Publications

The protein expression landscape of mitosis and meiosis in diploid budding yeast.

Becker Emmanuelle E   Com Emmanuelle E   Lavigne Régis R   Guilleux Marie-Hélène MH   Evrard Bertrand B   Pineau Charles C   Primig Michael M  

Journal of proteomics 20170103


Saccharomyces cerevisiae is an established model organism for the molecular analysis of fundamental biological processes. The genomes of numerous strains have been sequenced, and the transcriptome and proteome ofmajor phases during the haploid and diploid yeast life cycle have been determined. However, much less is known about dynamic changes of the proteome when cells switch from mitotic growth to meiotic development. We report a quantitative protein profiling analysis of yeast cell division an  ...[more]

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