Temporal quantitative proteomics of Chikungunya virus infected cells

ABSTRACT: To better understand the complex CHIKV-host interplay we used stable isotope labeling with amino acids in cell culture (SILAC) and LC-MS/MS to define the temporal dynamics of the cellular response to infection. Using samples harvested at 8, 10 and 12 hours post infection, over 4700 proteins were identified and per time point 2750-3150 proteins could be quantified in both biological replicates.

INSTRUMENT(S):

ORGANISM(S): Cercopithecidae (old World Monkeys)

TISSUE(S): Cell Culture

DISEASE(S): Chikungunya

SUBMITTER: Emmely Treffers  

LAB HEAD: Peter A van Veelen

PROVIDER: PXD001330 | Pride | 2015-03-16

REPOSITORIES: Pride