Dataset Information
PBC-DIGE - Serological comparative proteomics analysis of mitochondrial autoantibody-negative and -positive primary biliary cirrhosis
Ontology highlight
ABSTRACT:
NB Extra peak files are available on the FTP for this project .
INSTRUMENT(S): 4800 Proteomics Analyzer
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Blood Serum
SUBMITTER: 
Chuiwen Deng
LAB HEAD: Chuiwen Deng
PROVIDER: PXD001397 | Pride | 2014-11-27
REPOSITORIES: Pride
Publications
Serological comparative proteomics analysis of mitochondrial autoantibody-negative and -positive primary biliary cirrhosis.
Electrophoresis 20150612 14
Here, we investigated the pathogenesis of primary biliary cirrhosis (PBC) by using 2D-DIGE to analyze serological differences between anti-mitochondrial antibody (AMA)-positive and -negative PBC patients. The study comprised 30 patients with PBC; 20 AMA-positive and ten AMA-negative patients matched for age, sex, and pathological stage. A screening group (four AMA-positive and four AMA-negative patients) was used for 2D-DIGE. Protein spots that were differently abundant between the two groups we ...[more]
