Dataset Information
Global quantitative proteomics reveals novel factors in the ecdysone signaling pathway in Drosophila melanogaster.
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Drosophila Melanogaster (fruit Fly)
TISSUE(S): Permanent Cell Line Cell
SUBMITTER: 
Jeroen Demmers
LAB HEAD: Jeroen AA Demmers
PROVIDER: PXD001455 | Pride | 2015-01-23
REPOSITORIES: Pride
Publications
Global quantitative proteomics reveals novel factors in the ecdysone signaling pathway in Drosophila melanogaster.
Proteomics 20150114 4
The ecdysone signaling pathway plays a major role in various developmental transitions in insects. Recent advances in the understanding of ecdysone action have relied to a large extent on the application of molecular genetic tools in Drosophila. Here, we used a comprehensive quantitative SILAC MS-based approach to study the global, dynamic proteome of a Drosophila cell line to investigate how hormonal signals are transduced into specific cellular responses. Global proteome data after ecdysone tr ...[more]
