Proteomics

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Medicago truncatula drought stress recovery


ABSTRACT: Molecular Elasticity and Adjustment of Drought Recovery Dynamics of 14N- and 15N-fertilized Legume Medicago truncatula. Climate change in conjunction with population growth necessitates a systems biology approach to characterize plant drought response and a more thorough understanding of the underlying molecular mechanisms. During drought stress and recovery, the metabolome and proteome regulate and are regulated through diverse mechanisms including synthesis and degradation. In order to study this complex regulation network, a front-end multilevel analysis is presented for the first time, investigating protein turnover, regulatory classes of proteins and metabolites as well as post translational ubiquitination of a target set of proteins during a severe stress and recovery scenario in the model legume Medicago truncatula. Evidence for enhanced translational proteome regulation was observed during drought recovery and functional clusters of differentially dynamic phases during the course of recovery were defined. The data give novel insights into molecular elasticity that enable recovery of drought stressed plants. Additionally, these results offer putative targets and metabolic pathways for future plant-bioengineering towards enhanced drought stress tolerance.

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Medicago truncatula  

TISSUE(S): Root, Shoot

DISEASE(S): Not Available

SUBMITTER: David Lyon  

LAB HEAD: Stefanie Wienkoop

PROVIDER: PXD001728 | Pride | 2016-03-29

REPOSITORIES: pride

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Publications

Drought and Recovery: Independently Regulated Processes Highlighting the Importance of Protein Turnover Dynamics and Translational Regulation in Medicago truncatula.

Lyon David D   Castillejo Maria Angeles MA   Mehmeti-Tershani Vlora V   Staudinger Christiana C   Kleemaier Christoph C   Wienkoop Stefanie S  

Molecular & cellular proteomics : MCP 20160321 6


Climate change in conjunction with population growth necessitates a systems biology approach to characterize plant drought acclimation as well as a more thorough understanding of the molecular mechanisms of stress recovery. Plants are exposed to a continuously changing environment. Extremes such as several weeks of drought are followed by rain. This requires a molecular plasticity of the plant enabling drought acclimation and the necessity of deacclimation processes for recovery and continuous g  ...[more]

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