Ontology highlight
ABSTRACT:
INSTRUMENT(S): TripleTOF 5600
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Suspension Culture, Peripheral Blood Mononuclear Cell
SUBMITTER: Etienne Caron
LAB HEAD: Ruedi Aebersold
PROVIDER: PXD001904 | Pride | 2015-07-14
REPOSITORIES: Pride
Caron Etienne E Espona Lucia L Kowalewski Daniel J DJ Schuster Heiko H Ternette Nicola N Alpízar Adán A Schittenhelm Ralf B RB Ramarathinam Sri H SH Lindestam Arlehamn Cecilia S CS Chiek Koh Ching C Gillet Ludovic C LC Rabsteyn Armin A Navarro Pedro P Kim Sangtae S Lam Henry H Sturm Theo T Marcilla Miguel M Sette Alessandro A Campbell David S DS Deutsch Eric W EW Moritz Robert L RL Purcell Anthony W AW Rammensee Hans-Georg HG Stevanovic Stefan S Aebersold Ruedi R
eLife 20150708
We present a novel mass spectrometry-based high-throughput workflow and an open-source computational and data resource to reproducibly identify and quantify HLA-associated peptides. Collectively, the resources support the generation of HLA allele-specific peptide assay libraries consisting of consensus fragment ion spectra, and the analysis of quantitative digital maps of HLA peptidomes generated from a range of biological sources by SWATH mass spectrometry (MS). This study represents the first ...[more]