Proteomics

Dataset Information

0

Reanalysis of spike-in samples


ABSTRACT: Two samples in submission PXD001091 were reanalysed 22 months later on the same instrument.

INSTRUMENT(S): LTQ Orbitrap XL ETD

ORGANISM(S): Streptoccous Pyogenes

SUBMITTER: Fredrik Levander  

LAB HEAD: Fredrik Levander

PROVIDER: PXD002037 | Pride | 2015-04-20

REPOSITORIES: Pride

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Publications

Is label-free LC-MS/MS ready for biomarker discovery?

Sandin Marianne M   Chawade Aakash A   Levander Fredrik F  

Proteomics. Clinical applications 20150321 3-4


Label-free LC-MS methods are attractive for high-throughput quantitative proteomics, as the sample processing is straightforward and can be scaled to a large number of samples. Label-free methods therefore facilitate biomarker discovery in studies involving dozens of clinical samples. However, despite the increased popularity of label-free workflows, there is a hesitance in the research community to use it in clinical proteomics studies. Therefore, we here discuss pros and cons of label-free LC-  ...[more]

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