Glycoproteomic Analyses of Prostate Cancer Cells
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell
DISEASE(S): Prostate Adenocarcinoma
SUBMITTER: 
Paul Aiyetan
LAB HEAD: Hui Zhang
PROVIDER: PXD002107 | Pride | 2015-08-12
REPOSITORIES: Pride
Publications
Integrated Proteomic and Glycoproteomic Analyses of Prostate Cancer Cells Reveal Glycoprotein Alteration in Protein Abundance and Glycosylation.
Shah Punit P Wang Xiangchun X Yang Weiming W Toghi Eshghi Shadi S Sun Shisheng S Hoti Naseruddin N Chen Lijun L Yang Shuang S Pasay Jered J Rubin Abby A Zhang Hui H
Molecular & cellular proteomics : MCP 20150809 10
Prostate cancer is the most common cancer among men in the U.S. and worldwide, and androgen-deprivation therapy remains the principal treatment for patients. Although a majority of patients initially respond to androgen-deprivation therapy, most will eventually develop castration resistance. An increased understanding of the mechanisms that underline the pathogenesis of castration resistance is therefore needed to develop novel therapeutics. LNCaP and PC3 prostate cancer cell lines are models fo ...[more]
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