Proteomics

Dataset Information

0

Human milk whey proteins treated Caco-2 cells


ABSTRACT: Human milk whey proteins facilitate the development of enterocyte-like Caco-2 cells over time.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Epithelial Cell, Cell Culture

DISEASE(S): Disease Free

SUBMITTER: Qiang Zhang  

LAB HEAD: Qiang Zhang

PROVIDER: PXD002121 | Pride | 2015-11-23

REPOSITORIES: Pride

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Publications

Sensing Small Changes in Protein Abundance: Stimulation of Caco-2 Cells by Human Whey Proteins.

Cundiff Judy K JK   McConnell Elizabeth J EJ   Lohe Kimberly J KJ   Maria Sarah D SD   McMahon Robert J RJ   Zhang Qiang Q  

Journal of proteome research 20151215 1


Mass spectrometry (MS)-based proteomic approaches have largely facilitated our systemic understanding of cellular processes and biological functions. Cutoffs in protein expression fold changes (FCs) are often arbitrarily determined in MS-based quantification with no demonstrable determination of small magnitude changes in protein expression. Therefore, many biological insights may remain veiled due to high FC cutoffs. Herein, we employ the intestinal epithelial cell (IEC) line Caco-2 as a model  ...[more]

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