Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Urinary Bladder
DISEASE(S): Bladder Transitional Cell Carcinoma
SUBMITTER: Agnieszka Latosinska
LAB HEAD: Dr Antonia Vlahou
PROVIDER: PXD002170 | Pride | 2015-09-09
REPOSITORIES: Pride
Latosinska Agnieszka A Vougas Konstantinos K Makridakis Manousos M Klein Julie J Mullen William W Abbas Mahmoud M Stravodimos Konstantinos K Katafigiotis Ioannis I Merseburger Axel S AS Zoidakis Jerome J Mischak Harald H Vlahou Antonia A Jankowski Vera V
PloS one 20150902 9
High resolution proteomics approaches have been successfully utilized for the comprehensive characterization of the cell proteome. However, in the case of quantitative proteomics an open question still remains, which quantification strategy is best suited for identification of biologically relevant changes, especially in clinical specimens. In this study, a thorough comparison of a label-free approach (intensity-based) and 8-plex iTRAQ was conducted as applied to the analysis of tumor tissue sam ...[more]