Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Melanocyte, Cell Culture, Skin
DISEASE(S): Benign Skin Melanocytic Nevus,Metastatic Melanoma
SUBMITTER: Stephanie Byrum
LAB HEAD: Stephanie Byrum
PROVIDER: PXD002471 | Pride | 2015-12-02
REPOSITORIES: Pride
Sengupta Deepanwita D Byrum Stephanie D SD Avaritt Nathan L NL Davis Lauren L Shields Bradley B Mahmoud Fade F Reynolds Matthew M Orr Lisa M LM Mackintosh Samuel G SG Shalin Sara C SC Tackett Alan J AJ
Molecular & cellular proteomics : MCP 20151130 3
Normal cell growth is characterized by a regulated epigenetic program that drives cellular activities such as gene transcription, DNA replication, and DNA damage repair. Perturbation of this epigenetic program can lead to events such as mis-regulation of gene transcription and diseases such as cancer. To begin to understand the epigenetic program correlated to the development of melanoma, we performed a novel quantitative mass spectrometric analysis of histone post-translational modifications mi ...[more]