Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): T Cell, Jurkat Cell
DISEASE(S): Acute Leukemia
SUBMITTER: Tao Bing
LAB HEAD: Yinsheng Wang
PROVIDER: PXD002480 | Pride | 2022-02-28
REPOSITORIES: Pride
Molecular & cellular proteomics : MCP 20150721 10
Cancer biomarker discovery constitutes a frontier in cancer research. In recent years, cell-binding aptamers have become useful molecular probes for biomarker discovery. However, there are few successful examples, and the critical barrier resides in the identification of the cell-surface protein targets for the aptamers, where only a limited number of aptamer targets have been identified so far. Herein, we developed a universal SILAC-based quantitative proteomic method for target discovery of ce ...[more]