Ontology highlight
ABSTRACT:
INSTRUMENT(S): Synapt MS
ORGANISM(S): Rattus Norvegicus (rat)
TISSUE(S): Hepatocyte, Liver
SUBMITTER: Lucas Vu
LAB HEAD: Richard F. Helm
PROVIDER: PXD002491 | Pride | 2017-07-06
REPOSITORIES: Pride
Vu Lucas T LT Orbach Sophia M SM Ray W Keith WK Cassin Margaret E ME Rajagopalan Padmavathy P Helm Richard F RF
Proteome science 20160101
<h4>Background</h4>Liver models that closely mimic the in vivo microenvironment are useful for understanding liver functions, capabilities, and intercellular communication processes. Three-dimensional (3D) liver models assembled using hepatocytes and liver sinusoidal endothelial cells (LSECs) separated by a polyelectrolyte multilayer (PEM) provide a functional system while also permitting isolation of individual cell types for proteomic analyses.<h4>Methods</h4>To better understand the mechanism ...[more]