Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Jordy Hsiao
LAB HEAD: Michael, Eugene, Wright
PROVIDER: PXD002596 | Pride | 2015-09-03
REPOSITORIES: Pride
Hsiao Jordy J JJ Ng Brandon H BH Smits Melinda M MM Martinez Harryl D HD Jasavala Rohini J RJ Hinkson Izumi V IV Fermin Damian D Eng Jimmy K JK Nesvizhskii Alexey I AI Wright Michael E ME
Molecular endocrinology (Baltimore, Md.) 20150716 8
The aberrant expression of androgen receptor (AR)-dependent transcriptional programs is a defining pathology of the development and progression of prostate cancers. Transcriptional cofactors that bind AR are critical determinants of prostate tumorigenesis. To gain a deeper understanding of the proteins linked to AR-dependent gene transcription, we performed a DNA-affinity chromatography-based proteomic screen designed to identify proteins involved in AR-mediated gene transcription in prostate tu ...[more]