Comparative shotgun proteomics of aqueous humor for cataract, glaucoma and pseudoexfoliation eye disorders.
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
DISEASE(S): Glaucoma,Cataract,Exfoliation Syndrome
SUBMITTER: 
Irina Ilina
LAB HEAD: Sergey Moshkovskii
PROVIDER: PXD002623 | Pride | 2016-05-23
REPOSITORIES: Pride
Publications
Human aqueous humor proteome in cataract, glaucoma, and pseudoexfoliation syndrome.
Kliuchnikova Anna A AA Samokhina Nadezhda I NI Ilina Irina Y IY Karpov Dmitry S DS Pyatnitskiy Mikhail A MA Kuznetsova Ksenia G KG Toropygin Ilya Y IY Kochergin Sergey A SA Alekseev Igor B IB Zgoda Victor G VG Archakov Alexander I AI Moshkovskii Sergei A SA
Proteomics 20160701 13
Twenty-nine human aqueous humor samples from patients with eye diseases such as cataract and glaucoma with and without pseudoexfoliation syndrome were characterized by LC-high resolution MS analysis. In total, 269 protein groups were identified with 1% false discovery rate including 32 groups that were not reported previously for this biological fluid. Since the samples were analyzed individually, but not pooled, 36 proteins were identified in all samples, comprising the constitutive proteome of ...[more]
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