Comparative shotgun proteomics of aqueous humor for cataract, glaucoma and pseudoexfoliation eye disorders.

ABSTRACT: The aim of this work was to characterize proteome of aqueous humor from subjects with various eye conditions such as cataract, glaucoma and pseudoexfoliation syndrome by high-resolution chromate-mass-spectrometry. Twenty nine human aqueous humor samples were processed by shotgun proteomics. Data was searched using MaxQuant package. Totally, 263 protein groups were identified. Label-free quantitation reported some differentially expressed proteins in aqueous humor proteome for the aforementioned eye diseases.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

DISEASE(S): Glaucoma,Cataract,Exfoliation Syndrome

SUBMITTER: Irina Ilina  

LAB HEAD: Sergey Moshkovskii

PROVIDER: PXD002623 | Pride | 2016-05-23

REPOSITORIES: Pride