In vivo protein-protein interaction in C. elegans early embryos

ABSTRACT: We combine in vivo expressed GFP-tagged proteins with quantitative proteomics to identify protein-protein interactions of selected key proteins involved in early C. elegans embryogenesis. Co-affinity purification of interaction partners for eight bait proteins resulted in a pilot in vivo interaction map of proteins with a focus on early development.

INSTRUMENT(S):

ORGANISM(S): Caenorhabditis Elegans

TISSUE(S): Embryo

SUBMITTER: Jia-Xuan Chen  

LAB HEAD: Matthias Selbach

PROVIDER: PXD002624 | Pride | 2016-02-29

REPOSITORIES: Pride