Pseudomonas aeruginosa cystic fibrosis strains share a core proteome
Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA295120PRJNA295121PRJNA295123PRJNA295122
INSTRUMENT(S): TripleTOF 5600
ORGANISM(S): Pseudomonas Aeruginosa Pao1
TISSUE(S): Cell Culture
DISEASE(S): Cystic Fibrosis
SUBMITTER: 
Christoph Krisp
LAB HEAD: Ian Paulsen
PROVIDER: PXD002865 | Pride | 2015-10-14
REPOSITORIES: Pride
Publications
Genetically and Phenotypically Distinct Pseudomonas aeruginosa Cystic Fibrosis Isolates Share a Core Proteomic Signature.
Penesyan Anahit A Kumar Sheemal S SS Kamath Karthik K Shathili Abdulrahman M AM Venkatakrishnan Vignesh V Krisp Christoph C Packer Nicolle H NH Molloy Mark P MP Paulsen Ian T IT
PloS one 20151002 10
The opportunistic pathogen Pseudomonas aeruginosa is among the main colonizers of the lungs of cystic fibrosis (CF) patients. We have isolated and sequenced several P. aeruginosa isolates from the sputum of CF patients and compared them with each other and with the model strain PAO1. Phenotypic analysis of CF isolates showed significant variability in colonization and virulence-related traits suggesting different strategies for adaptation to the CF lung. Genomic analysis indicated these strains ...[more]
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