Analysis of skeletal muscle from a tailored pig model of Duchenne muscular dystrophy

ABSTRACT: We recently generated a novel genetically engineered pig model displaying the fundamental biochemical, clinical and pathological hallmarks of human DMD. To get insight into the hierarchy of molecular derangements during progression of muscular dystrophy, we performed a label free proteome analysis of biceps femoris muscle samples from 2-day-old and 3-month-old DMD and WT pigs.

INSTRUMENT(S):

ORGANISM(S): Sus Scrofa Domesticus (domestic Pig)

TISSUE(S): Biceps Femoris

DISEASE(S): Duchenne Muscular Dystrophy

SUBMITTER: Thomas Fröhlich  

LAB HEAD: Thomas Fröhlich

PROVIDER: PXD002918 | Pride | 2016-09-27

REPOSITORIES: Pride