Human DNA Mismatch Repair pathway LC-MSMS

ABSTRACT: The mismatch repair (MMR) family is a highly conserved group of proteins that function in correcting base-base and insertion-deletion mismatches generated during DNA replication. To systematically investigate the mismatch repair pathway, we conducted a proteomic analysis and identified MMR-associated protein complexes using a tandem-affinity purification coupled with mass spectrometry (TAP-MS) method. In total, we identified 262 high-confidence candidate interaction proteins (HCIPs).

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture, Early Embryonic Cell, Kidney

SUBMITTER: Zhen Chen  

LAB HEAD: Junjie Chen

PROVIDER: PXD003014 | Pride | 2016-02-08

REPOSITORIES: Pride