Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell, Cell Culture
DISEASE(S): Non-small Cell Lung Carcinoma
SUBMITTER: Akhilesh Pandey
LAB HEAD: Akhilesh Pandey
PROVIDER: PXD003108 | Pride | 2016-12-14
REPOSITORIES: Pride
Raja Remya R Sahasrabuddhe Nandini A NA Radhakrishnan Aneesha A Syed Nazia N Solanki Hitendra S HS Puttamallesh Vinuth N VN Balaji Sai A SA Nanjappa Vishalakshi V Datta Keshava K KK Babu Niraj N Renuse Santosh S Patil Arun H AH Izumchenko Evgeny E Prasad T S Keshava TS Chang Xiaofei X Rangarajan Annapoorni A Sidransky David D Pandey Akhilesh A Gowda Harsha H Chatterjee Aditi A
Oncotarget 20160901 38
Epidemiological data clearly establishes cigarette smoking as one of the major cause for lung cancer worldwide. Recently, targeted therapy has become one of the most preferred modes of treatment for cancer. Though certain targeted therapies such as anti-EGFR are in clinical practice, they have shown limited success in lung cancer patients who are smokers. This demands discovery of alternative drug targets through systematic investigation of cigarette smoke-induced signaling mechanisms. To study ...[more]