Proteomic analysis of clear cell renal cell carcinoma tissue versus matched normal kidney tissue

ABSTRACT: We analyzed 84 tumor/normal pairs (177 total) using standard shotgun proteomic techniques in order to characterize the molecular landscape of clear cell renal cell carcinoma (ccRCC) and interrogated changes in protein abundance and biological pathways with ccRCC grade. These tissues were distributed across stage 1 (n = 34), 2 (n = 40), 3 (n = 42), and 4 (n = 52), with 9 pairs also including samples from metastasized tumor. These data can be (and were) combined with a previously published transcriptomic data set from the same sample cohort (NCBI GEO: GSE53757).

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Kidney

DISEASE(S): Renal Clear Cell Carcinoma

SUBMITTER: Benjamin Neely  

LAB HEAD: Richard R. Drake

PROVIDER: PXD003271 | Pride | 2016-04-18

REPOSITORIES: Pride