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The proteomics analysis of Crassostrea gigas under Zn and Cd contamination

ABSTRACT: Understanding organisms’ environmental adaptation mechanisms is a fundamental question in ecology and evolution. The oyster Crassostrea gigas is able to accumulate high levels of zinc (Zn) and cadmium (Cd) without self-poisoning, and is thus widely used for pollution detection. However, the molecular mechanisms underlying such stress adaptation are largely unknown. Therefore, this study aimed to provide fundamental insights into the complex Zn/Cd-response regulatory networks.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Crassostrea Gigas (pacific Oyster) (crassostrea Angulata)

TISSUE(S): Gill

SUBMITTER: Jie Meng

LAB HEAD: Jie Meng

PROVIDER: PXD003290 | Pride | 2018-10-25

REPOSITORIES: Pride

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Cadmium effects on DNA and protein metabolism in oyster (Crassostrea gigas) revealed by proteomic analyses.

Meng Jie J Wang Wenxiong W Li Li L Yin Qi Q Zhang Guofan G

Scientific reports 20170915 1

Marine molluscs, including oysters, can concentrate high levels of cadmium (Cd) in their soft tissues, but the molecular mechanisms of Cd toxicity remain speculative. In this study, Pacific oysters (Crassostrea gigas) were exposed to Cd for 9 days and their gills were subjected to proteomic analysis, which were further confirmed with transcriptomic analysis. A total of 4,964 proteins was quantified and 515 differentially expressed proteins were identified in response to Cd exposure. Gene Ontolog ...[more]

PMID: 28916745

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