Dataset Information
N-glyco db/db mouse kidney - N-glycosylation proteome enrichment analysis in kidney reveals differences between diabetic mouse models
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Elite
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Kidney
DISEASE(S): Diabetic Nephropathy
SUBMITTER: 
Leena Liljedahl
LAB HEAD: Peter James
PROVIDER: PXD003349 | Pride | 2016-12-13
REPOSITORIES: Pride
Publications
N-glycosylation proteome enrichment analysis in kidney reveals differences between diabetic mouse models.
Clinical proteomics 20161015
<h4>Background</h4>Diabetic nephropathy (DN) is a late complication in both type 1 diabetes mellitus (T1DM) and T2DM. Already at an early stage of DN morphological changes occur at the cell surface and in the extracellular matrix where the majority of the proteins carry N-linked glycosylations. These glycosylated proteins are highly important in cell adhesion and cell-matrix processes but not much is known about how they change in DN or whether the distinct etiology of T1DM and T2DM could have a ...[more]
