Dataset Information

Proteomic analysis of the gametocyte secretome

ABSTRACT: in this study we analysed the gametocyte secretome and osmiophilic body proteins by mass spectrometry

INSTRUMENT(S): LTQ Orbitrap, LTQ Orbitrap Elite

ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress)

TISSUE(S): Blood Cell, Blood

DISEASE(S): Plasmodium Falciparum Malaria

SUBMITTER: Bernd Hessling

LAB HEAD: Friedrich Frischknecht

PROVIDER: PXD003487 | Pride | 2016-07-05

REPOSITORIES: Pride

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Publications

Proteomic Analysis of the Plasmodium berghei Gametocyte Egressome and Vesicular bioID of Osmiophilic Body Proteins Identifies Merozoite TRAP-like Protein (MTRAP) as an Essential Factor for Parasite Transmission.

Kehrer Jessica J Frischknecht Friedrich F Mair Gunnar R GR

Molecular & cellular proteomics : MCP 20160701 9

Malaria transmission from an infected host to the mosquito vector requires the uptake of intraerythrocytic sexual precursor cells into the mosquito midgut. For the release of mature extracellular gametes two membrane barriers-the parasite parasitophorous vacuole membrane and the host red blood cell membrane-need to be dissolved. Membrane lysis occurs after the release of proteins from specialized secretory vesicles including osmiophilic bodies. In this study we conducted proteomic analyses of th ...[more]

PMID: 27371728

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Dataset Information

Proteomic analysis of the gametocyte secretome

Publications

Proteomic Analysis of the Plasmodium berghei Gametocyte Egressome and Vesicular bioID of Osmiophilic Body Proteins Identifies Merozoite TRAP-like Protein (MTRAP) as an Essential Factor for Parasite Transmission.

Similar Datasets

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