Proteomics

Dataset Information

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Mouse gut metaproteome - MetaPro-IQ: a universal metaproteomic approach to studying human and mouse gut microbiota


ABSTRACT: The mouse stool samples were collected from different diets fed mice and bacterial cells were harvest for metaproteomic analysis for understanding the role ofdiet on gut microbiota.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Mouse Gut Metagenome

SUBMITTER: Xu Zhang  

LAB HEAD: Daniel Figeys

PROVIDER: PXD003527 | Pride | 2016-07-05

REPOSITORIES: Pride

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Publications


<h4>Background</h4>The gut microbiota has been shown to be closely associated with human health and disease. While next-generation sequencing can be readily used to profile the microbiota taxonomy and metabolic potential, metaproteomics is better suited for deciphering microbial biological activities. However, the application of gut metaproteomics has largely been limited due to the low efficiency of protein identification. Thus, a high-performance and easy-to-implement gut metaproteomic approac  ...[more]

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